Meaning

• To make unclean, dirty, or impure; soil; befoul.

• To vandalize or add inappropriate contents to something considered sacred or special; desecrate

  "To urinate on someone's grave is an example of a way to defile it."

• To deprive or ruin someone's (sexual) purity or chastity, often not consensually; stain; tarnish; mar; rape

  "The serial rapist kidnapped and defiled a six-year-old girl."